Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts.
It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy.
HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits.
The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).
A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Applications:Suitable for use in ELISA (solid phase immobilization) in very sensitive and specific gold assays.
Recommended Dilution:Sensitivity: 10mIU/ml in 3 minutes: Gold-membrane sandwichOptimal dilution determined by the researcher.
Matched Pairs:Capture: C5069-54Detection: C5069-66ASuitable for use as the capture or solid phase antibody
Matched to C5069-81 as the detection or conjugate (label) antibody.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:1mg
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity:Recognizes hCGa: 100%.Species Crossreactivity: Alpha specific, reacts with LH, hCG, FSH and prolactin.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Hu
Immunogen:Purified Human Chorionic Gonadotropin, alpha