Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts.
It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy.
HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits.
The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).
A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Applications:Suitable for use in RIA.
Other applications not tested.
Recommended Dilution:RIA: 100,000 tests/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C or colder.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:1ml
Host:rabbit
Source Antibody:human
Grade:Serum
Purity:Supplied as a sterile-filtered, defibrinated neat serum.