T cell activation via anti-CD3 & anti-CD28 signals, along with anti-CD2 & anti-CD137, all presented on the AimGel artificial cell platform. AimGel's fluid lipid membrane enables gentle and effective activation of T cells from isolated T cells and PBMC.
Aim-Tconv is a suspension of hydrogel microparticles (HMP) designed for robust activation and expansion of human pan T cells. Aim-Tconv HMP are designed to self-degrade in approximately 14 days under culture environment. For any downstream processing (e.g. counting, flow cytometry) and if earlier removal of Aim-Tconv HMP is desired, please remove using the digesting buffer provided in the kit.
Components:A suspension of hydrogel microparticles (HMP) made of chemically crosslinked dextran. HMPs sized 6-15 μm were coated with phospholipid bilayer, with membrane docked T cell activating signal panels (CD2, CD3, CD28, CD137).・1 vial of Aim-Tconv HMP in PBS (4 × 107 beads / mL) with 0.5% P/S.・1 vial of HMP digesting buffer (20X, 1.0mL).