Discription：FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Mature human FGF-21 respectively shows 81％ a.a. identity to murine and rat FGF-21, and is known to be active on murine cells. Recombinant Human FGF-21 is a 19.4kDa protein containing 181 amino acid.
