Discription：Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 （TRAIL-R2） is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand （TRAIL） -induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients. Recombinant Human soluble TRAILR2/TNFRSF10B is a 14.8kDa protein （132 amino acid） consisting of the TNFR-homologous, cysteine-rich portion of the extracellular domain.
