Discription:Murine CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Murine CCL11 is approximately 63% identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60% amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor. Recombinant Murine Eotaxin/CCL11 is an 8.4kDa protein containing 74 amino acid residues.