Discription：Human CCL13 is belonging to the CC chemokine family and is encoded by the gene CCL13 in humans. CCL13 （MCP-4） shares 56-61％ sequence identity with MCP-1 （CCL2） and MCP-3 （CCL7） and is 60％ identical to Eotaxin （CCL11） . CCL13 was a potent chemoattractant for monocytes and eosinophils and stimulated histamine release from basophils. CCL13 can induce a calcium flux in HEK-293 cells transfected with the receptor CCR2B and CCR3. That shows the function receptors of CCL3 are CCR2B and CCR3. Recombinant human MCP-4/CCL13 is an 8.6kDa protein containing 75 amino-acid residues including the four highly conserved cysteine residues present in the CC chemokines.
