Discription：Fibroblast Growth Factor 4 （FGF-4, also named FGFK and KFGF） belongs to the large FGF family which has at least 23 members. FGF-4 has functions that maintain a population of progenitor cells in the epiblast that generates mesoderm, and contribute to the stem cell population that is incorporated in the tailbud. It is also required for axial elongation of the mouse embryo after gastrulation. Mature human FGF4 shares 91％, 82％, 94％ and 91％ a.a. identity with murine, rat, canine and bovine FGF4. Additionally, FGF-4 shares about 30％ sequence identity with the prototypical members of the FGF family. Recombinant human FGF-4 is a 19.8kDa protein containing 182 amino-acid residues.
