Discription:Serum amyloid A-1 protein which belongs to the SAA family is encoded by the SAA1 gene in humans. It is expressed by the liver and secreted in plasma. Serum amyloid A-1 is the major acute phase reactant and apolipoprotein of the HDL complex. Elevated serum SAA1 protein levels may be associated with lung cancer. The level of Apo-SAA1, normally 1-5ug/ml in plasma, increases 500-1000fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. Recombinant human Apo-SAA1 is an 11.7kDa protein containing 104 amino acid residues.