The protein encoded by this gene is a member of the TNF-receptor superfamily.
This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response.
This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation.
This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.