The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells.
Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self.
The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family.
The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.