This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain.
It is included in a cluster of homeobox B genes located on chromosome 17.
The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development.
Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.