This gene encodes cytochrome c, a component of the electron transport chain in mitochondria.
The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex.
Cytochrome c is also involved in initiation of apoptosis.
Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9.
Many cytochrome c pseudogenes exist, scattered throughout the human genome.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.