Pre-mRNA splicing occurs in two sequential transesterification steps.
The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process.
It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions.
This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression.
It suggests that this protein may play a role in cell cycle progression.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.