This protein belongs to the aldehyde dehydrogenases family of proteins.
It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo.
This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal.
Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal.
Two transcript variants encoding distinct isoforms have been identified for this gene.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.