The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family.
AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors.
They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.
This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Alternatively splice transcript variants encoding distinct isoforms have been described.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.