Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol.
This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Applications:Suitable for use in ELISA, Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500
仕様
Size:200ul
抗体種類:Pab
宿主:mouse
Source Antibody:human
Grade:Purified
Purity:Purified by Euglobin precipitation followed by dialysis against PBS.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human MAP3K13.
Isotype:IgG
Calc Applications Abbrev:IF WB
Calc Crossreactivity:Hu
Immunogen:Purified protein corresponding to aa52-305 from human MAP3K13, fused to His-Tag.