83-6077-22　TFPI (EPI, LACI, TFI, TFPI1) 50ug　470179

特徴

• This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation.
• The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot.
• The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
• The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
• Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTII TDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTR QCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIK TTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCER FKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYG TQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGL CRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQ ECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF VKNM
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.