83-6076-82　RING1 (RING1A, RNF1) 50ug　470138

特徴

• This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain.
• The gene product can bind DNA and can act as a transcriptional repressor.
• It is associated with the multimeric polycomb group protein complex.
• The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains.
• It interacts with the CBX4 protein via its glycine-rich C-terminal domain.
• The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHR FCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFD ALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEE GLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGE GEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSV GTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPS PPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVK TTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGG ASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVS EKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPL ELCYAPTKDPK
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.