83-6076-71　PROM1 (AC133, CD133, MSTP061, PROmL1, RP41) 50ug　470125

特徴

• This gene encodes a pentaspan transmembrane glycoprotein.
• The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation.
• Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease.
• Expression of this gene is also associated with several types of cancer.
• This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner.
• Multiple transcript variants encoding different isoforms have been found for this gene.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MALVLGSLLLLGLCGNSFSGGQPSSTDAPKAWNYELP ATNYETQDSHKAGPIGILFELVHIFLYVVQPRDFPEDTL RKFLQKAYESKIDYDKIVYYEAGIILCCVLGLLFIILMPLV GYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISL LVICIIISIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRT LLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLGGGILD RLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQ QSTQLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIR LSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLV QQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDN VTQRLPIQDILSAFSVYVNNTESYIHRNLPTLEEYDSYW WLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRG CVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANV EKLICEPYTSKELFRVLDTPYLLNEDWEYYLSGKLFNK SKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNI NEHTGSISSELESLKVNLNIFLLGAAGRKNLQDFAACGI DRMNYDSYLAQTGKSPAGVNLLSFAYDLEAKANSLPP GNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKIL QRTGNGLLERVTRILASLDFAQNFITNNTSSVIIEETKKY GRTIIGYFEHYLQWIEFSISEKVASCKPVATALDTAVDV FLCSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYRR MDSEDVYDDVETIPMKNMENGNNGYHKDHVYGIHNP VMTSPSQH
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.