The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides.
Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQ KIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLV AYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPK KRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENI RQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKR YCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTM GYSVTAPEDTRRICELLFS
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human PMM2
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-246 from full length human PMM2.
