83-6074-95　CDH12 (CDHB, FLJ34857) 50ug　469941

特徴

• This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
• Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
• Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
• This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MLTRNCLSLLLWVLFDGGLLTPLQPQPQQTLATEPRE NVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQ YVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDI HAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQ DINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDAD DPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALPNMD REVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVND NPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNAE IEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKK AYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDE PPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAV RYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYN FSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAV CENAKPGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKP NFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDS SYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGL STGALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSKEDI RDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENKIRR DIKPDSLCLPRQRPPMEDNTDIRDFIHQRLQENDVDPT APPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDY LTDWGPRFKVLADMFGEEESYNPDKVT
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.