83-6074-89　CCNF (FBX1, FBXO1) 50ug　469935

特徴

• This gene encodes a member of the cyclin family.
• Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases.
• This member also belongs to the F-box protein family which is characterized by an approximately 40aa motif, the F-box.
• The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
• The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
• The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPE DVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWAC ASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYN EGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWL FIRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILH CLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLL WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLS LAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQV FSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVE CVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIRE AVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDY KEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARL AAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVL SLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQ EEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSP SGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETLLG SFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVT VVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDT QIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSS VDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQ CRPPSPPESSVPQQQVKRINLCIHSEEEDMNLGLVRL
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.