The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases.
Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.
These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle.
This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta).
The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes.
This gene encodes a beta 3 subunit.
This gene encodes a beta 3 subunit.
A pseudogene exists for this gene, and it is located on chromosome 2.
[provided by RefSeq]
Applications:Suitable for use in Flow Cytometry, Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWG LILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQI PSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFL KPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQ ACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRID CVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYL QPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDR DKFLGRVMFKITARA
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid. No preservative added.
Specificity：Recognizes human ATP1B3
Isotype：IgG
Calc Applications Abbrev：FC WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-279 from full length human ATP1B3.
