83-6074-55　AOC2 (DAO2, RAO) 50ug　469901

特徴

• Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor.
• This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals.
• The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper.
• It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.
• This gene may be a candidate gene for hereditary ocular diseases.
• Alternate splicing results in multiple transcript variants.
• [provided by RefSeq]
• Applications:Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSV SHRAQPWPHPGQSQLFADLSREELTAVMRFLTQRLG PGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGS PPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRD VTVERHGGPLPYHRRPVLRAEFTQMWRHLKEVELPK APIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMAL YHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYL GHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRS RNSPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFG HGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPK TMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHI LVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFY GGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRV HATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAF HFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQ RPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAW GHQRGYRIQIHSPLGIHIPLESDMERALSWGRYQLVVT QRKEEESQSSSIYHQNDIWTPTVTFADFINNETLLGED LVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFF DEDPSIFSPGSVYFEKGQDAGLCSINPVACLPDLAACV PDLPPFSYHGF
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.