Pre-mRNA splicing is catalyzed by the spliceosome.
U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence.
U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron.
The protein encoded by this gene contains a RNA recognition motif.
It was identified as one of the protein components of U11/U12 snRNPs.
This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns.
These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
Applications:Suitable for use in Immunofluorescence, Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Ascites
Purity：Ascites
Form：Supplied as a liquid. No preservative added.
Specificity：Recognizes human ZCRB1.
Isotype：IgG
Calc Applications Abbrev：IF WB
Calc Crossreactivity：Hu
Immunogen：Full length protein corresponding to aa1-217 of human ZCRB1.
