83-6068-80　TP53I3 (Tumor Protein p53 Inducible Protein 3, PIG3) 50ug　252908

特徴

• The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation.
• This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.
• It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.
• P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence.
• The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53.
• It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
• At least two transcript variants encoding the same protein have been found for this gene.
• [provided by RefSeq
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQMouse polyclonal antibody raised against a full-length human TP53I3 protein.IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGMouse polyclonal antibody raised against a full-length human TP53I3 protein.GFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.