The protein encoded by this gene is a Ro RNP-binding protein.
It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.
This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.
It can repress a c-myc reporter via the FUSE.
It is also known to target transcription factor IIH and inhibit activated transcription.
This gene is implicated in the xeroderma pigmentosum disorder.
There are two alternatively spliced transcript variants of this gene encoding different isoforms.
There seems to be evidence of multiple polyadenylation sites for this gene.
[provided by RefSeq
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MATATIALQVNGQQGGGSEPMouse polyclonal antibody raised against a full-length human SIAHBP1 protein.AAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPMouse polyclonal antibody raised against a full-length human SIAHBP1 protein.VMouse polyclonal antibody raised against a full-length human SIAHBP1 protein.AATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Ascites
Purity：Ascites
Form：Supplied as a liquid. No preservative added.
Specificity：Recognizes human SIAHBP1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：SIAHBP1 (NP_510965, 1aa-559aa) full-length human protein.
