In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens.
It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone.
However, the enzyme has some reductive activity and can synthesize estradiol from estrone.
The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily.
An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
[provided by RefSeq
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRMouse polyclonal antibody raised against a full-length human HSD17B8 protein.QETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQMouse polyclonal antibody raised against a full-length human HSD17B8 protein.QALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human HSD17B8.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：HSD17B8 (NP_055049.1, 1aa-261aa) full-length human protein.
