Tis7, also known as IFRD1, is a 442aa containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family.
A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF.
Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes.
Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.
Applications:Suitable for use in Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 10ug/ml
仕様
Size：50ug
抗体種類：Pab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2.
Specificity：Recognizes human IFRD1.
Isotype：IgG
Calc Applications Abbrev：IF WB
Calc Crossreactivity：Hu
Immunogen：Full length human IFRD1, aa1-451 (AAH01272.1).
