83-6009-05 MXD4 (Max Dimerization Protein 4, Max Dimerizer 4, Max-interacting Transcriptional Repressor MAD4, Max-associated Protein 4, Class C Basic Helix-loop-helix Protein 12, bHLHc12, MAD4) 50ug 130029
83-6009-05 MXD4 (Max Dimerization Protein 4, Max Dimerizer 4, Max-interacting Transcriptional Repressor MAD4, Max-associated Protein 4, Class C Basic Helix-loop-helix Protein 12, bHLHc12, MAD4) 50ug 130029
The MAD, basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex.
The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex.
Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
抗体種類:Pab
宿主:mouse
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Recognizes human MXD4.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Full-length human MXD4, aa1-209 (NP_006445.1).