83-6008-07　MNDA (Myeloid Cell Nuclear Differentiation Antigen) 50ug　129773

特徴

• The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage.
• A 200aa region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon inducible mouse genes, designated Ifi 201, Ifi 202, and Ifi 203, that are not regulated in a cell or tissue specific fashion.
• The 1.8kb MNDA mRNA, which contains an interferon stimulated response element in the 5 prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha.
• MNDA is located within 2,200kb of FCER1A, APCS, CRP, and SPTA1.
• In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell specific responses to interferons.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Immunohistochemistry (FFPE): 3ug/mlOptimal dilutions to be determined by the researcher.
• Amino Acid Sequence:MVNEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIKITDLMEKKFQGVACLDKLIELAKDMPSLKNLVNNLRKEKSKVAKKIKTQEKAPVKKINQEEVGLAAPAPTARNKLTSEARGRIPVAQKRKTPNKEKTEAKRNKVSQEQSKPPGPSGASTSAAVDHPPLPQTSSSTPSNTSFTPNQETQAQRQVDARRNVPQNDPVTVVVLKATAPFKYESPENGKSTMFHATVASKTQYFHVKVFDINLKEKFVRKKVITISDYSECKGVMEIKEASSVSDFNQNFEVPNRIIEIANKTPKISQLYKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGKWHNIKCEKGDKLRLFCLQLRTVDRKLKLVCGSHSFIKVIKAKKNKEGPMNVN
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.