The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription.
SP110 is a member of the SP100/SP140 family of nuclear body proteins and a leukocyte-specific nuclear body component.
The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator.
In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.
Applications:Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Immunofluorescence: 10ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 3ug/mlOptimal dilutions to be determined by the researcher.