83-6000-87　GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16) 50ug　127413

特徴

• Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells.
• Differentiation of promyelocytic cells leads to decreased expression of Ga16.
• The G protein is known to couple a large number of G protein-coupled receptors to PLC-b and can lead to production of the secondary messengers diacylglycerol and inositol phosphates.
• Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling.
• Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.