83-5986-44　BST2 (Bone Marrow Stromal Antigen 2, BST-2, HM1.24 Antigen, Tetherin, CD317) 50ug　B3000-08C

特徴

• Bone marrow stromal Antigen-2 (BST-2) is a 30-36kD type II transmembrane protein, consisting of 180aa.
• BST-2 protein is expressed on certain bone marrow stromal cell lines and on various normal tissues.
• The expression pattern of BST2 is relatively different form another bone marrow stromal antigen 1 (BST1).
• The BST-2 gene is located on chromosome 19p13.2.
• BST-2 surface expression on fibroblast cell lines facilitated the stromal cell-dependent growth of a murine bone marrow-derived pre-B-cell line, DW34.
• Some studies suggest that BST-2 may be involved in pre-B-cell growth development by regulating their surface molecules and cytokines.
• BST2 is also expressed in bone marrow stromal cell lines and synovial cell lines from where the BST2 gene was cloned.
• BST2 is predominantly expressed in liver, lungs, heart, placenta and lower levels in pancreas, kidney, skeletal muscle and brain.
• Applications:Suitable for use in Western Blot, Immunohistochemistry (paraffin), and Immunofluorescence.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.