83-5985-87　Interleukin 9, Recombinant Human (IL-9) 2ug　I8431

特徴

• IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes.
• IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines.
• Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease.
• Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells.
• Recombinant human IL-9 is a 14.kD protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.
• Recombinant protein corresponding to human IL-9, expressed in E.
• coli.
• Amino Acid Sequence:MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCLGIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVEVLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKMRGMRGKI
• Biological Activity:Determined by its ability to stimulate the proliferation of human MO7e cells.
• The expected ED50 is <0.2ng/ml, corresponding to a specific activity of >5x10e6units/mg.
• Storage and Stability:Lyophilized and reconstituted products are stable for 6 months after receipt at -20℃.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.