83-5985-80　EGF, Recombinant, Human, Animal Free (Epidermal Growth Factor, Urogastrone, URG) 500ug　E3410

特徴

• EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells.
• Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing.
• EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor.
• This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).
• Recombinant human EGF is a 6.2kD globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds.
• Recombinant protein corresponding to human EGF expressed in E.
• coli.
• Biological Activity:The EC50, as determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1ng/ml, corresponding to a specific activity of ≥1x10e7 units/mg.
• Aminp Acid Sequence:NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR
• Storage and Stability:Lyophilized and reconstituted products are stable for 6 months after receipt at -20℃.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.