OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family.
It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts.
It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand / TNFSF4 that is expressed by antigen presenting cells.
OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells.
OX40 is upregulated at the sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.
Applications:Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence and Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 1-2ug/ml/10e6 cellsELISA: CoatingImmunofluorescence: 1-2ug/mlImmunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT.
Requires HIER
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS. No preservative added.
Specificity：Recognizes the human CD134.
Clone # USB：OX40/3108
Isotype：IgG2c,k
Calc Applications Abbrev：E FC IF IHC
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to a portion of amino acids 95-205 from human CD134.
