Lymphotoxin beta receptor is 385 amino acid (415 aa including 30 aa signal peptide) ~50kD type 1, single pass transmembrane glycoprotein and member of the tumor necrosis factor family.
LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines.
052562 is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlgans et al.
2003).
052562 is routinely tested on WEH164S cells.
Applications:Suitable for use in Flow Cytometry and Functional Assays.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Hybridoma:SP2/0-Ag14 myeloma cells with spleen cells from Wistar rats.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：500ug
抗体種類：Mab
宿主：rat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography from tissue culture supernatant.
Form：Supplied as a liquid in PBS. No preservative added.
Specificity：Recognizes mouse surface expressed LT beta R.
Clone # USB：5G11b
Isotype：IgG2a
Calc Applications Abbrev：FC
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to the extracellular domain of mouse LT beta R
