CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus.
Human CLIC5 is transcribed in two isoforms, 32kD CLIC5a (251 amino acids) and 49kD CLIC5b (410 amino acids).
These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo.
CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.
Applications:Suitable for use in Flow Cytometry and Western Blot.