CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling.
CD203c is expressed mainly on activated basophils and mast cells.
CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis.
Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.
Applications:Suitable for use in Flow Cytometry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 20ul labels 10e6 cells of 100ul whole blood or 1x10e6 cells in suspension.
Extracellular and intracellular staining
Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Highly Purified
Purity：Purified by size-exclusion chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes human CD203C.
Clone # USB：NP4D6
Isotype：IgG1
Calc Applications Abbrev：FC IC
Calc Crossreactivity：Hu
Immunogen：HEK-293 cells transfected with human CD203c
