CD36 (fatty acid translocase, FAT) is an 88kD ditopic glycosylated protein that belongs to the class B family of scavenger receptors.
CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on follicular B cells in vitro upon TLR and CD40 stimulation.
CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response.
Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin.
In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 20ul labels 10e6 cells or human blood cells in 100ul whole blood.
Optimal dilutions to be determined by the researcher.
Excitation Laser:Blue (488nm)
Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
Aliquots are stable at -20℃ for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Highly Purified
Purity：Purified by size-exclusion chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Specificity：Recognizes an extracellular epitope of human CD36. Cross-blocks binding of FITC-labeled standard antibody OKM5.
