Adiponectin is a fat-derived hormone which suppresses glucose production in the liver and enhances fatty acid oxidation in skeletal muscle, and acts as a messenger to allow communication between adipose tissue and other organs (Wang and Scherer, 2016).
Adiponectin can elicit several downstream signaling events, including the insulin signaling pathway.
Anti-diabetic, anti-inflammatory, and anti-atherogenic effects of adiponectin have been identified, and the protein sensitizes cells to insulin.
Decreased adiponecin levels may play a role in development of type 2 diabetes, and therefore, adiponectin has been suggested as a potential therapeutic target for diabetes (Achari and Jain 2017).
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilution:ELISA: 1ug/ml
Optimal dilutions to be determined by the researcher.
Hybridoma:Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Matched Pair:Capture: 052309Detection: 052310
Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
Aliquots are stable at -20℃ for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G chromatography from tissue culture supernatant.
Form：Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide. Labeled with Biotin.
Specificity：Recognizes human Adiponectin.
Clone # USB：D02-7B10
Isotype：IgG1
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Glu19-Asn244 from human Acrp30, expressed in E. coli.
