Adiponectin is a fat-derived hormone which suppresses glucose production in the liver and enhances fatty acid oxidation in skeletal muscle, and acts as a messenger to allow communication between adipose tissue and other organs (Wang and Scherer, 2016).
Adiponectin can elicit several downstream signaling events, including the insulin signaling pathway.
Anti-diabetic, anti-inflammatory, and anti-atherogenic effects of adiponectin have been identified, and the protein sensitizes cells to insulin.
Decreased adiponecin levels may play a role in development of type 2 diabetes, and therefore, adiponectin has been suggested as a potential therapeutic target for diabetes (Achari and Jain 2017).
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilution:ELISA: 1ug/mlOptimal dilutions to be determined by the researcher.
Hybridoma:Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Matched Pair:Capture: 052309Detection: 052310
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G chromatography from tissue culture supernatant.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human Adiponectin.
Clone # USB：D05-9C7
Isotype：IgG1
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Glu19-Asn244 from human Acrp30, expressed in E. coli.
