Anchors the extracellular matrix to the cytoskeleton via F-actin.
Ligand for dystroglycan.
Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.
Also implicated in signaling events and synaptic transmission.
Application:Suitable for use in Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:200-1:1:000Immunohistochemistry: 1:200-1:6000 (ABC detection) is recommended to detect dystrophin fresh frozen, or acetone fixed, 2% PLP fixed sections.
Not recommended for paraffin embedded tissues
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20℃.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ul
抗体種類:Mab
宿主:mouse
Source Antibody:human
Grade:Ascites
Purity:Ascites
Form:Supplied as a powder lyophilized from 1.2% sodium acetate, 2% BSA, 0.01% sodium azide. Reconstitue with 1mL sterile PBS.
Specificity:Recognizes human Dystrophin. Species Crossreactivity: mouse, rat, rabbit and chicken.
Clone # USB:8H11/MANDYS8
Isotype:IgG2b
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Ch Hu Mo Rb Rt
Immunogen:Recombinant protein corresponding to aa816-1749 from human dystrophin.