83-5981-46　CD274 (Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, B7-H1, B7H1, PDCD1L1, PDCD1LG1, PDL1) (FITC) 100Tests　052118-FITC

特徴

• CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins.
• It can act as both costimulatory and coinhibitory molecule for T cells.
• Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection.
• Even pathogens (e.g.
• Schistosoma) may exploit CD274 to evade an immune response.
• Besides CD279, existence of other receptor(s) for CD274 is likely.
• Applications:Suitable for use in Flow Cytometry.
• Other applications not tested.
• Recommended Dilutions:Flow Cytometry: 4ul labels 100ul whole blood or 10e6 cells in a suspension
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
• Aliquots are stable at -20℃ for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.