83-5981-45　CD274 (Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, B7-H1, B7H1, PDCD1L1, PDCD1LG1, PDL1) 100ug　052118

特徴

• CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins.
• It can act as both costimulatory and coinhibitory molecule for T cells.
• Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection.
• Even pathogens (e.g.
• Schistosoma) may exploit CD274 to evade an immune response.
• Besides CD279, existence of other receptor(s) for CD274 is likely.
• Applications:Suitable for use in Flow Cytometry and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Flow Cytometry: 1-4ug/ml
• Immunohistochemistry: frozen (acetone fixation)
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.