CD303 is an ~38kD type II transmembrane glycoprotein with an extracellular C-type lectin domain.
It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells.
CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Applications:Suitable for use in ELISA, Flow Cytometry, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: frozenFlow Cytometry: 1-5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
Specificity：Recognizes human CD303
Clone # USB：15E3
Isotype：IgG1,k
Calc Applications Abbrev：E FC IC IHC
Calc Crossreactivity：Hu
Immunogen：CD303 ectodomain fused with human IgG Fc domain
