83-5981-07 CD18 (Leukocyte Function Associated Antigen, LFA-1 beta2, ITGB2) (Low Endotoxin) 100ug 052043
特徴
- CD18 associates with CD11a to form a heterodimeric adhesion molecule known as Lymphocyte Function Associated Antigen-1 (LFA-1).
- LFA-1 binds to the intracellular adhesion molecule-1 (ICAM-1, CD54).
- CD18 also associates with CD11b and CD11c.
- CD11b and CD18 form the complex known as Mac-4.
- CD18 and CD11c form a complex that binds to fibrogen and iC3b.
- Applications:Suitable for use in Functional Applications, Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilutions:Western Blot (non-reducing conditions): 2ug/mlFlow Cytometry: 2ug/mlImmunohistochemistry (paraffin sections): 10ug/mlImmunohistochemistry: frozenFunctional Application: induces high-affinity conformation of LFA-1 complex
- Optimal dilutions to be determined by the researcher.
- WB Positive Control:Kg-1a human leukemia cell lysate
- IHC Positive Control:Human spleen, microglia
- Storage and Stability:May be stored at 4℃ for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20℃.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- 抗体種類:Mab
- 宿主:mouse
- Source Antibody:human
- Grade:Purified
- Purity:Purified
- Form:Supplied as a liquid in PBS, pH 7.4. No preservative added.
- Specificity:Recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the human CD18 antigen. Does not react with canine.
- Clone # USB:MEM-48
- Isotype:IgG1
- Calc Applications Abbrev:FC IHC IP WB
- Calc Crossreactivity:Hu
- Immunogen:Leukocytes of a patient suffering from a LGL-type leukemia.
- Swiss Prot Number:P05107
- EU Commodity Code:30021010
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