CD361, also known as EVI2B (ecotropic viral integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene.
The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1.
Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias.
CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation.
However, it is expressed mainly in peripheral blood and bone marrow.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 20ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Excitation Laser:Blue (488 nm)
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size:100Tests
抗体種類:Mab
宿主:mouse
Source Antibody:human
Grade:Purified
Purity:Purified by size-exclusion chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity:Recognizes an extracellular epitope of human CD361